G6PD deficiency; potential folate deficiency; hepatic and renal impairment; elderly; porphyria; thyroid dysfunction; maintain adequate hydration.
Adult: PO Tablet : 2 tablet twice daily. In severe cases, 3 times/day. DS Tablet : 1 tablet twice daily.
Suspension : 1-2 teaspoonful twice daily.
GI infections; Resp and urinary tract infections; Susceptible infections 960 mg twice daily, up to 2.88 g/day in 2 divided doses for severe cases.
Pneumocystis (carinii) jiroveci pneumonia Up to 120 mg/kg/day in 2-4 divided doses for 14-21 days. Infection prophylaxis in AIDS patients 960 mg/day.
Child: 6 wk-5 mth: 120 mg bid; 6 mth-5 yr: 240 mg bid; 6-12 yr: 480 mg bid.
Renal impairment: Dosage reduction for adults and children >12 yr:
15-30 Half the standard dose.
<15 Not recommended.