It should be given with caution to patients with impaired kidney function or severe liver damage. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.
It should not exceed 0.5-1 g/kg body weight per hour. The usual recommended flow rate for adult is 30-75 drops per minute infused intravenously.